College of American Pathologists Conference XXXI on Laboratory Monitoring of Anticoagulant Therapy: Introduction From: Archives of Pathology & Laboratory Medicine | Date: September 1, 1998| Author: | Copyright College of American Pathologists Sep 1998. Provided by ProQuest LLC.Copyright information

Thromboembolism is a common clinical problem that is associated with serious morbidity and mortality if not appropriately treated. For nearly 50 years, the therapy of venous thromboembolism has centered around the use of heparin and warfarin. Use of these agents has always presented a double-edged sword; too little anticoagulation is associated with a higher risk of recurrent thrombosis, while too much anticoagulation is associated with a higher risk of bleeding. Thus, laboratory tests were introduced at an early point to monitor the therapy of these 2 agents; indeed, laboratory monitoring of ...

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