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Primary pulmonary pleomorphic adenoma: An immunohistochemical study and review of the literature
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* Primary pleomorphic adenoma of the lung is an uncommon condition. We present a case of primary pulmonary pleomorphic adenoma and its immunohistologic features. The presence of immunoreactivity to both anticytokeratin and antivimentin antibodies for its epithelial components is suggestive of a primary pulmonary lesion. Its high proliferation index and its immunoreactivity to tumor regulatory gene p16(INK4A) are features that, to our knowledge, have not been reported previously. They may have...
Related newspaper, magazine, and journal articles from HighBeam Research
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Primary pulmonary pleomorphic adenoma: An immunohistochemical study and review of the literature
Archives of Pathology & Laboratory Medicine
; * Primary pleomorphic adenoma of the lung is an uncommon condition. We present a case of primary pulmonary pleomorphic adenoma and its immunohistologic features. The presence of immunoreactivity to both anticytokeratin and antivimentin antibodies for its epithelial components is suggestive of a
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ELEVATED EXPRESSION OF CYCLOOXYGENASE-2 IN ADENOCARCINOMA OF THE PAROTID GLAND: INSIGHTS INTO MALIGNANT TRANSFORMATION OF PLEOMORPHIC ADENOMA
The Annals of Otology, Rhinology & Laryngology
; Pleomorphic adenoma, the most common type of tumor of the parotid gland, may transform into a malignant tumor. In the current study, we investigated whether the expression of cyclooxygenase-2 (COX-2) is elevated in adenocarcinoma as compared to pleomorphic adenoma. Ten pleomorphic adenomas and 10
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PLEOMORPHIC ADENOMA OF THE NASAL SEPTUM
The Annals of Otology, Rhinology & Laryngology
; Pleomorphic adenoma may occur in any site in which there is salivary gland tissue. It has rarely been described arising in the nasal cavity. We report a case of septal pleomorphic adenoma and discuss the clinical presentation and surgical management. KEY WORDS - pleomorphic adenoma, septum. CASE
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Pleomorphic adenoma of the parotid.
American Family Physician
; Pleomorphic adenomas are the most common type of salivary gland tumor. Consequently, primary care physicians need to know how to diagnose and manage these lesions, which most often occur in the parotid gland. Appropriate management is crucial: these tumors can be cured if they are correctly
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Pleomorphic adenoma of the breast: A case report and distinction from mucinous carcinoma
Archives of Pathology & Laboratory Medicine
; Pleomorphic adenoma of the breast is a rare, benign tumor accounting for 68 cases in the literature. It is most commonly seen in postmenopausal women and is characterized by an admixture of epithelial and myoepithelial cells embedded in abundant myxomatous stroma. Its clinical and histologic
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Worrisome histologic alterations following fine-needle aspiration of benign parotid lesions
Archives of Pathology & Laboratory Medicine
; Objective.-To describe the histologic changes associated with preoperative fine-needle aspiration biopsies of benign parotid lesions and the features that distinguish these changes from malignant neoplasms. Materials and Methods.-Ten benign parotid lesions with a recent history of preoperative
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Primary pulmonary hypertension. (Tips from Other Journals)
American Family Physician
; Primary pulmonary hypertension is a diagnosis of exclusion: if a careful workup reveals no cardiac, pulmonary or systemic cause, the condition is designated as primary pulmonary hypertension (see table). Palevsky and Fishman review the management of this syndrome, including some investigational
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Recurrent pleomorphic adenoma of the parotid gland involving the osseous external auditory canal: With a note on the foramen of Huschke
The Annals of Otology, Rhinology & Laryngology
; A recurrence of a parotid pleomorphic adenoma presenting as an external ear canal mass is reported. The route of extension was radiographically documented as an incompletely closed foramen of Huschke. The historical and developmental features of this foramen and the mechanisms of tumor extension as
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Expensive drug thwarts deadly lung ailment. (epoprostenol, or prostacyclin, is very effective against primary pulmonary hypertension)(Brief Article)
Science News
; Only 15 years ago, primary pulmonary hypertension was inevitably fatal. The disease stems from blockages of the arteries that deliver blood to the lungs. Blood pressure builds in these arteries, making it difficult for the right side of the heart to pump. What starts as shortness of breath leads to
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True malignant mixed tumor (carcinosarcoma) of parotid gland with unusual mesenchymal component: A case report and review of the literature
Archives of Pathology & Laboratory Medicine
; * True malignant mixed tumor (carcinosarcoma) of the salivary gland is an extremely rare tumor. By definition, it is composed of both malignant epithelial and malignant mesenchymal elements. The most common type of the former is squamous cell carcinoma or adenocarcinoma and the most common type of
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