Evaluation of DNA dosimetry to assess ozone-mediated variability of biologically harmful radiation in Antarctica

From: Photochemistry and Photobiology | Date: September 1, 2002| Author: | Copyright information

Evaluation of DNA Dosimetry to Assess Ozone-Mediated Variability of Biologically Harmful Radiation in Antarctica(para)

ABSTRACT

In this study we investigated the use of a DNA dosimeter to accurately measure changes in ultraviolet B radiation (UVBR; 280-315 nm) under Antarctic ozone hole conditions. Naked DNA solution in quartz tubes was exposed to ambient solar radiation at Rothera Research Station, Antarctica, between October and December 1998 for 3 h during UVBR peak hours (1200-1500 h). Trends in UVBR-mediated DNA damage (formation of cyclobutane pyrimidine dimers [CPD]) were related to ...

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