Catecholamine-synthesizing enzymes in carcinoid tumors and pheochromocytomas

Clinical Chemistry | April 1, 2003| | Copyright

5 Nonstandard abbreviations: AADC, aromatic-L-amino acid decarboxylase; APUD, amine precursor uptake and decarboxylation; MEN, multiple endocrine neoplasia; TH, tyrosine hydroxylase; DBH, dopamine-beta-hydroxylase; PNMT, phenylethanolamine-N-methyltransferase; 5-HIAA, 5-hydroxyindoleacetic acid; URL, upper reference limit; PBS, phosphate-buffered saline; and BSA, bovine serum albumin.

Background: Serotonin is the principal endocrine product of carcinoid tumors, but simultaneously increased production of catecholamines has been described in these tumors. As it is not clear whether these ...

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