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Probing the cell peripheral movements by optical trapping technique
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ABSTRACT Swiss 3T3 fibroblasts cultured on a poly-L-lysine-coated coverslip was stimulated with 0.5 (mu)M phorbol myristate acetate, and the movements of the peripheral membranes were probed with a 1-(mu)m polystyrene bead held in an optical trap. The bead brought into contact with the cell edge occasionally moved away from and returned to the original position. The movement ranged over 100 nm and occurred mainly in one direction, suggesting that the protruding cell membrane pushed the bead. The maximum velocities derived from individual pairs of protrusive and withdrawal movements exhibited ...
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Lipid Vesicles as Membrane Models for Toxicological Assessment of Xenobiotics
; ...have long been appreciated as simple cell membrane models in biochemical and biophysical...Antimicrobial Peptides, Antibiotics, Cell Membrane Damage, Xenobiotics, Phospholipids...INTRODUCTION The basic structure of the cell membrane has many sites for toxicant action...
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Imaging Single Virus Particles on the Surface of Cell Membranes by High-Resolution Scanning Surface Confocal Microscopy
; ...experiments we have demonstrated that the cell membrane exhibits numerous submicrometer-sized...single polyoma VLPs adsorbed onto the cell membrane. Observed VLPs had a mean width of...were randomly distributed across the cell membrane, and no specific interactions were...
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P.S. I love you: Implications of phosphatidyl serine (PS) reversal in acute ischemic syndromes
; ...pyrophosphate require loss of integrity of the cell membrane to achieve localization. Annexin AS...proceeds, evaginations develop in the cell membrane. These are brought about by random...cytoskeletal proteins. Blebs develop in the cell membrane, and the fragments of cytoplasmic ...
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ELECTROMECHANICAL: Berkeley Sounds Biochemical Alarm.
; ...changes in the electrical resistance of a cell membrane within milliseconds after it is exposed...The electrodes continuously probe the cell membrane and track the amount of electrical...Rubinsky. It occurred to us that when the cell membrane breaks, it would allow various ions...
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Stochastic Entry of Enveloped Viruses: Fusion versus Endocytosis
; ...binding of receptors on the target cell membrane to glycoproteins, or "spikes," on the...simultaneously initiate direct fusion with the cell membrane. Both fusion and internalization have...nonspecifically adsorbed on the host cell membrane are computed as functions of receptor...
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Laser beam triggers a membrane breach. (laser used to induce expulsion of structures within cell without damaging cell membrane or structures)(Brief Article)
; The cell membrane serves as a tough, flexible barrier that protects a cell from its...low-power laser beam focused on an artificial structure that mimics a cell membrane can trigger the spontaneous ejection of material inside without permanently...
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Transient Confinement Zones: A Type of Lipid Raft?
; ...signaling events are initiated at the cell membrane. To facilitate efficient signal transduction...Singer-Nicolson fluid mosaic model, the cell membrane is considered as a 2-D oriented solution...gold particles to molecules on the cell membrane, the dynamics of a small number of...
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MIT reveals inner lives of red blood cells.(Research News)
; ...Spectroscopy Laboratory are able to see cell membrane vibrations as tiny as a few tens of nanometers. Studying cell membrane dynamics can help scientists gain...sickle cell anemia and cancer. Cell membrane dynamics are just the beginning...
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Electrochemotherapy delivers drugs to tumors
; Bleomycin able to successfully permeate cell membrane, bind to DNA, and destroy tumor cells...because they cannot get through the cell membrane. The drug is not as effective because...researchers thought, would make the cell membrane more permeable by exposing it to electric...
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Elastic thickness compressibilty of the red cell membrane
; ...thickness compressibility of the red cell membrane in situ. Pushed into the centers of...structure. INTRODUCTION The red blood cell membrane is one of the most thoroughly researched...two-dimensional projection of the red cell membrane architecture and material properties...
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