The acrodermatitis enteropathica mutation affects protein expression in human fibroblasts: Analysis by two-dimensional gel electrophoresis

From: The Journal of Nutrition | Date: August 1, 1998| Author: | Copyright information

The Acrodermatitis Enteropathica Mutation Affects Protein Expression in Human Fibroblasts: Analysis by Two-Dimensional Gel Electrophoresis1,2,3

(Manuscript received 26 February 1998. Initial review completed 13 April 1998. Revision accepted 19 May 1998.) Arthur Grider4 and Michael F. Mouat

ABSTRACT The acrodermatitis enteropathica (AE) mutation affects zinc uptake in human fibroblasts. However, the specific biochemical lesion has not been identified. We have used the technique of two-dimensional gel electrophoresis to identify protein differences in total cell lysate isolated from normal ...

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