Prediction of urinary excretion of technetium-99m-MAG3

The Journal of Nuclear Medicine | July 1, 1998| | Copyright

The urinary excretion of 9Tc-mercaptotriacetylglycine (MAG3), like that of '3'1-orthoiodohippurate (OIH), can be used to identify acute renal transplant rejection and measure its severity. This parameter is often quantitated as the excretory index (observed excretion/predicted excretion). A new method for predicting the urinary excretion of 99mTc-MAG3 is presented. Methods: The expected excretion was calculated from multisample plasma timeactivity curves in 122 subjects, with correction for the first pass of the initial bolus. The resulting formula was tested prospectively against actual ...

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