Genetics of suicidal behavior: Candidate association genetic approach

From: The Israel Journal of Psychiatry and Related Sciences | Date: January 1, 2002| Author: | Copyright information

Abstract: Suicidal behavior runs in families and seemed to be genetically determined in part and independent of the presence of psychiatric disorders. This review presents the current knowledge of candidate gene association studies in the field of suicidology. Concordance for monozygotic twins is about 13% Vs. 0.7% in dizygotics. It seems that there is a relationship to intermediate phenotypes such as impulsivity and aggression. The problem of studying complex traits and of ethnic stratification in heterogeneous population are major concerns in studying genetics of suicide. Family-based ...

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