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Therapeutic delivery issues in gene therapy, part 2: Targeting approaches
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Successful gene therapy requires reliable delivery of genes to the desired cell type. Part 2 concludes this article with a discussion of issues relating to gene delivery strategies.
Vector selection is an important aspect of gene therapy and must take into account the properties of the vector, the intended target, and the desired length of expression. Part 1 (BioPharm March issue) of this article discussed issues relating to nonvector, viral, and nonviral delivery strategies and explored the current literature in those areas. Part 2 continues that discussion and looks at targeting ...
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