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Leptin suppresses food intake and body weight in corticosterone-replaced adrenalectomized rats
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Nutritional Neurosciences
Leptin Suppresses Food Intake and Body Weight in Corticosterone-- Replaced Adrenalectomized Rats1,2
ABSTRACT Intracerebroventricular (ICV) injections of leptin decrease food intake and body weight while increasing energy expenditure. Some of these effects are reportedly enhanced in bilaterally adrenalectomized (ADX) rats. The purpose of the present experiment was to establish the time course of the suppression in body weight and food intake after an ICV injection of leptin. We wanted to establish the effect of varying doses of corticosterone (CORT) on body weight ...
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