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Pharmacological doses of some synthetic retinoids can modulate both the aryl hydrocarbon receptor and retinoid receptor pathways
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Pharmacological Doses of Some Synthetic Retinoids Can Modulate Both the Aryl Hydrocarbon Receptor and Retinoid Receptor Pathways1,2
ABSTRACT Retinoids have been demonstrated to have pharmacological application in the areas of dermatology and oncology. In addition to the natural retinoids such as all-trans-retinoic acid and 9-cis-retinoic acid, many new potential retinoid drugs have been synthesized, including retinoic acid receptor (RAR)-subtype selective agonists, retinoid X receptor...