Copper deficiency induces the upregulation of the copper chaperone for Cu/Zn superoxide dismutase in weanling male rats

The Journal of Nutrition | January 1, 2003| | Copyright

Biochemical and Molecular Actions of Nutrients Research Communication

Copper Deficiency Induces the Upregulation of the Copper Chaperone for Cu/Zn Superoxide Dismutase in Weanling Male Rats1

(Manuscript received 7 August 2002. Initial review completed 27 August 2002. Revision accepted 23 October 2002.)

ABSTRACT The most commonly used indices for determining copper deficiency in humans are reduced serum/ plasma copper concentration and decreased activity of ceruloplasmin and Cu/Zn superoxide dismutase (SOD1). However, these indicators are influenced by many factors unrelated to copper ...

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