Biologic responses to low does of ionizing radiation: Adaptive response versus bystander effect / Reply

From: The Journal of Nuclear Medicine | Date: January 1, 2003| Author: Adelstein, S James; Feinendegen, Ludwig E; Pollycove, Myron | Copyright information

TO THE EDITOR: In their Newsline commentary, Drs. Feinendegen and Pollycove call an important issue to the attention of readers of The Journal of Nuclear Medicine (1). In a discussion of the dual action of ionizing radiation, they posit a competition at low doses between the direct induction of radiation damage and the activation of damage control (adaptive response, hormesis), such that below 0.2 Gy the frequency of oncogenic transformation is lower than background and net radiation damage d...

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