Catecholamine-induced T-wave lability in congenital long QT syndrome: A novel phenomenon associated with syncope and cardiac arrest

Mayo Clinic Proceedings | January 1, 2003| | Copyright

Original Article

* Objective: To determine the effects of phenylephrine and dobutamine on repolarization ]ability in patients with genotyped long QT syndrome (LQTS).

* Patients and Methods: Between December 1998 and August 2000,23 patients with genotyped LQTS (13 LQT1, 7 LQT2, and 3 LQT3) and 16 controls underwent electrocardiographic stress testing at the Mayo Clinic in Rochester, Minn. Aperiodic repolarization lability was quantified from digitized electrocardiograms recorded during catecholamine stress testing with phenylephrine and dobutamine. T-wave lability was quantified as a ...

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