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Genotoxicity of waste anaesthetic gases
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SUMMARY
Background and aim: The possibility of a potential mutagenic or carcinogenic action of chronic exposure to low concentrations of inhalational anaesthetics has been previously studied, with conflicting results. The purpose of this study was to assess whether occupational exposure to waste anaesthetic gases increases genotoxic risk. We examined peripheral lymphocytes from anaesthetists for both sister chromatid exchange (SCE) and for cells with high-frequency SCEs (HFCs).
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Related newspaper, magazine, and journal articles from HighBeam Research
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Genotoxicity of waste anaesthetic gases
Anaesthesia and Intensive Care
; SUMMARY Background and aim: The possibility of a potential mutagenic or carcinogenic action of chronic exposure to low concentrations of inhalational anaesthetics has been previously studied, with conflicting results. The purpose of this study was to assess whether occupational exposure to waste
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RELATIONSHIP BETWEEN OCCUPATIONAL EXPOSURE TO ANAESTHETIC GASES AND SPONTANEOUS ABORTION
Gynecological Endocrinology
; P149 Background: There are different opinions about the relationship between the exposure of pregnant staff members to anaesthetic gases and the occurance of spontaneous abortion. the purpose of this study was to determine the relationship between the exposure to anaesthetic gases and occurance of
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Relationship between occupational exposure to anaesthetic gases and spontaneous abortion
European Journal of Contraception & Reproductive Health Care
; SESSION 1: ABORTION Introduction: There are different opinions about the relationship between the exposure of pregnant staff members to anaesthetic gases and the occurance of spontaneous abortion. Objective: The purpose of this study was to determine the relationship between the exposure to
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Effect of nitric oxide and malondialdehyde on sister-chromatid exchanges in breast cancer
British Journal of Biomedical Science
; Abstract: Nitric oxide (NO) and malondialdehyde (MDA) play a significant role in DNA damage, sister-chromatid exchanges (SCEs) and carcinogenesis. Here, we determine plasma NO and MDA to evaluate their role in carcinogenesis and their effect on the frequency of SCEs in 45 female breast cancer
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Chromosomal aberrations and chronic low-level radiation exposure
The Journal of Nuclear Medicine
; Brazilian researchers reported in December that chronic exposure to low-level ionizing radiation may cause chromosomal aberrations and sister chromatid exchanges in health care workers. Reporting in Teratogenesis, Carcinogenesis, and Mutagenesis (2001;21:431-439) Cardoso et al. of the Universidade
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The Protease Activity of Yeast Separase (Esp1) Is Required for Anaphase Spindle Elongation Independently of Its Role In Cleavage of Cohesin
Genetics
; ABSTRACT Separase is a caspase-family protease required for the metaphase-anaphase transition in eukaryotes. In budding yeast, the separase ortholog, Esp1, has been shown to cleave a subunit of cohesin, Mcd1 (Scc1), thereby releasing sister chromatids from cohesion and allowing anaphase. However,
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Arabidopsis Separase AESP Is Essential for Embryo Development and the Release of Cohesin during Meiosis
Plant Cell
; To investigate how and when sister chromatid cohesion is released from chromosomes in plants, we isolated the Arabidopsis thaliana homolog of separase (AESP) and investigated its role in somatic and meiotic cells. AESP is similar to separase proteins identified in other organisms but contains
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Methylphenidate is linked to increases in cell abnormalities.(Behavioral Pediatrics)
Pediatric News
; Methylphenidate is associated with significant increases in cell abnormalities when given to children at therapeutic levels, reported Dr. Randa E1Zein of the University of Texas M.D. Anderson Cancer Center and colleagues. Data from 12 children showed significant increases in several genotoxic end
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Interchromatid and Interhomolog Recombination in Arabidopsis thaliana
Plant Cell
; Intermolecular recombination events were monitored in Arabidopsis thaliana lines using specially designed recombination traps consisting of tandem disrupted [beta]-glucuronidase or luciferase reporter genes in direct repeat orientation. Recombination frequencies (RFs) varied between the different
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Disruption of Topoisomerase II Perturbs Pairing in Drosophila Cell Culture
Genetics
; ABSTRACT Homolog pairing refers to the alignment and physical apposition of homologous chromosomal segments. Although commonly observed during meiosis, homolog pairing also occurs in nonmeiotic cells of several organisms, including humans and Drosophila. The mechanism underlying nonmeiotic pairing,
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