Clinicopathological consultation: Syndrome of inappropriate antidiuretic hormone secretion associated with head and neck cancers: Review of the literature

The Annals of Otology, Rhinology & Laryngology | October 1, 1997| | Copyright

In a minority of patients with malignant tumors, signs and symptoms develop that cannot be explained on the basis of the mass effect produced by the primary tumor or its metastases, or production of a hormone normally associated with the tissue type that has given rise to the malignant tumor; these peculiar symptom complexes are known as paraneoplastic syndromes, and may be divided into endocrinologic, dermatologic, hematologic, neurologic, and osteoarticular manifestations. In the head and neck region in particular, the syndrome of inappropriate antidiuretic hormone production (SIADH, or ...

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