Unsaturated fatty acids associated with glycogen may inhibit glucose-6 phosphatase in rat liver

The Journal of Nutrition | December 1, 1997| | Copyright

Unsaturated Fatty Acids Associated with Glycogen May Inhibit Glucose-6 Phosphatase in Rat Livere1,2,3

Nathalie Daniele,4 Jean-Claude Bordet* and Gilles Mithieux5

Institut National de la Sante et de la Recherche Medicale, Unites 449 and 331, Faculte de Medecine R. Laennec, 69372 Lyon Cedex 08, France

ABSTRACT This study was conducted to identify the nature of a glycogen-associated compound that had been shown to inhibit glucose-6 phosphatase in vitro. Glycogen was purified from the liver of fed rats by potassium hydroxyde digestion and ethanol precipitation. It inhibited glucose-6 ...

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