In vivo dopamine metabolism is altered in iron-deficient anemic rats

The Journal of Nutrition | December 1, 1997| | Copyright

In Vivo Dopamine Metabolism Is Altered in Iron-Deficient Anemic Rats1

Christopher Nelson,2 Keith Erikson, Domingo J. Pinero and John L. Beard3

ABSTRACT Previous studies of dopamine metabolism in iron-deficient rats demonstrated an elevation in extraneuronal levels of dopamine and a depression in the number of dopamine D6sub 2^ receptors; however, the importance of anemia per se and the reversibility of these observations are not completely resolved. The purpose of this study was to determine if in vivo reuptake of caudate dopamine is altered by iron deficiency anemia, if it is reversible ...

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