High-dose glucocorticoids inhibit proliferation of rat olfactory epithelium

The Annals of Otology, Rhinology & Laryngology | October 1, 2002| | Copyright

Glucocorticoids (GCs) are commonly prescribed for treatment of olfactory dysfunction. However, the effects of GCs on olfactory epithelium are not well known. We investigated the effects of high-dose GCs on proliferating cells of olfactory epithelium. Five adult male rats (300 g) received a single daily subcutaneous dose of vehicle containing 0.3 mg dexamethasone (DEX) for 9 days (DEX+ group), and a control group received vehicle alone (DEX- group). We compared sections from the two groups for numbers of Ki67-positive cells. The mean number of Ki67-positive cells per 500 olfactory epithelial ...

Read all of this article with a FREE trial to HighBeam Research

Related newspaper, magazine, and trade journal articles from HighBeam Research

(Including press releases, facts, information, and biographies)

II Serpente di Bronzo.(Sound recording review)
Magazine article from: Czech Music ; ...Potrei sovra degli empi is not entirely congenial to the this singer's natural temperament, and so the raging Old Testament Jahve inevitably has less of a choleric presence than the composer probably intended. Nonetheless one can only take off one's hat...

Find more facts and information related to the article "High-dose glucocorticoids inhibit proliferation ..."