Treatment of vocal fold scarring: Rheological and histological measures of homologous collagen matrix

From: The Annals of Otology, Rhinology & Laryngology | Date: October 1, 2002| Author: Thibeault, Susan L; VanGroll, Patrick J; Kriesel, Kevin J; Chan, Roger W; Et al | Copyright information

The current treatment options for dysphonia secondary to vocal fold scarring are limited. Few studies address changes in the lamina propria, which is critical to vocal fold biomechanical properties and voice production. Using rheological and histological measures of homologous collagen matrix (HCM)-injected vocal folds, we assessed HCM's potential for providing bulk and restoring biomechanical performance. Twenty rabbits underwent bilateral vocal fold scarring. After 10 weeks of scar maturati...