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Increased Glucose Availability Activates Chicken Thymocyte Metabolism and Survival1
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Abstract
Glucose metabolism in mammalian thymocytes is coupled to their development and selection in the thymus. In chickens, thymocytes develop in a low glucose concentration in ovo and a high glucose concentration posthatch. To determine the effect of glucose concentration on thymocyte glucose metabolism, embryonic thymic lobes were cultured in media containing varying glucose concentrations and thymocytes were isolated for analysis. Glucose transporter-1 (Glut-1) and Glut-3 mRNA abundance was at least 2-fold higher in thymocytes incubated with 10 and 20 mmol/L glucose than in those ...
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Notch Protein Signaling Directs Early T-Cell Development; Better Grasp of Immune Cell Lineages May Improve Outcomes for Transplant, Other Immunosuppressed Patients.
News Wire article from: Ascribe Higher Education News Service
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EBV latent membrane protein 2A triggers CD5+ B[subscript]1 cell development.
Newspaper article from: Drug Week
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News Wire article from: US Fed News Service, Including US State News
; ...press release: General Motors' Fuel Cell Development Center in Honeoye Falls opened in...in the world. Most of GM's fuel cell development activities occur at this Monroe County...for GM to reach its goal. The Fuel Cell Development Center is responsible for the development...
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Newspaper article from: Immunotherapy Weekly
; ...has dose-dependent effects on T-cell development. To determine the role of IL-7...overexpression, showed enhanced alphabeta T-cell development," reported N. El Kassar and coauthors...founder line, TgB, alphabeta T-cell development was disturbed with a block at the...
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Newspaper article from: Immunotherapy Weekly
; ...glucocorticoid receptor (GR) signaling in T cell development is highly controversial, with several...lung development, exhibit normal T cell development, at least in embryonic mice and in...the role of GR signaling in adult T cell development, we analyzed the few GR...
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Newspaper article from: Biotech Week
; ...HOX) genes play a key role in T cell development. These genes "comprise a large family...expression or function during T-cell development is limited." "Using degenerated...cluster genes during intrathymic T-cell development and an unexpected expression of HOX...
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Newspaper article from: Health & Medicine Week
; ...by the IL-7R are required for B-cell development," immunologists in the United States...pathways in IL-7R-dependent B-cell development," C.A. Goetz and colleagues at...background fails to rescue B-cell development. In contrast, STAT5 activation selectively...
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Newspaper article from: Immunotherapy Weekly
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Newspaper article from: Hematology Week
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Newspaper article from: Virus Weekly
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