Influence of L-Thyroxine Therapy on Parathyroid Hormone Concentrations

Clinical Chemistry | June 1, 2008| | Copyright

To the Editor:

In our RIA laboratory, we serendipitously observed that an unusual number of patients referred from the outpatient endocrinology clinic of the St. Savas Oncology Hospital had parathyroid hormone (PTH) concentrations exceeding the recommended upper reference limit of 6.90 pmol/L (65 ng/L) of our assay (ELSA-PTH, Cisbio International). Further work-up failed to show any evidence for hyperparathyroidism, but these patients were all receiving L-thyroxine for various thyroid problems, and their thyrotropin (TSH) concentrations were very suppressed (<0.4 mIU/L).

To investigate ...

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