Genetic Expectations of Quantitative Trait Loci Main and Interaction Effects Obtained With the Triple Testcross Design and Their Relevance for the Analysis of Heterosis

From: Genetics | Date: April 1, 2008| Author: | Copyright information

ABSTRACT

Interpretation of experimental results from quantitative trait loci (QTL) mapping studies on the predominant type of gene action can be severely affected by the choice of statistical model, experimental design, and provision of epistasis. In this study, we derive quantitative genetic expectations of (i) QTL effects obtained from one-dimensional genome scans with the triple testcross (TTC) design and (ii) pairwise interactions between marker loci using two-way analyses of variance (ANOVA) under the F^sub 2^- and the F∞-metric model. The theoretical results show that genetic ...

Related newspaper, magazine, and trade journal articles from HighBeam Research

(Including press releases, facts, information, and biographies)

The Role of Epistasis in the Manifestation of Heterosis: A Systems-Oriented Approach
; ...heterosis on the basis of different modes of gene action such as dominance, overdominance, and...experiments investigating these types of gene action (for review see Lynch andWalsh 1998...relative importance of different types of gene action is the analysis of generation means...
Consumers Urged to say No to GMOs: Theeeey're Gross!
; ...Stapleton, one of the organizers of Gene Action, a Toronto-based group fighting to get...awareness here is on the rise. When Gene Action started leafletting in January, she...After Super Bug's antics, members of Gene Action and Nuna Robinson from the Canadian...
Genetic influences on late-life diseases
; ...Evolutionary theory predicts two categories of gene action that modulate differential susceptibility...polymorphisms. Mutations. The first category of gene action involves rare mutations that are thought...Polymorphisms. The other relevant category of gene action involves ...
(book reviews)
; ...very theoretical bent, chapter nine, Gene Action and Plant Breeding , challenges readers...reexamine traditional explanations of simple gene action at a single locus or at interacting...understanding of the real nature of gene action. Chapters six and seven, provide comprehensive...
Agronomic performance of hybrids between cultivars and chromosome substitution lines.
; ...only determine additive or epistatic gene action because the lines are homozygous. To detect dominant gene action, hybrids or their segregating progeny...overcome this limitation. Dominant gene action is important because hybrid wheat...
Both Costs and Benefits of Sex Correlate With Relative Frequency of Asexual Reproduction in Cyclically Parthenogenic Daphnia pulicaria Populations
; ...population. However, when nonadditive gene action is involved, sex can actually impede...population. In addition, when nonadditive gene action underlies a quantitative trait, sex...Feldman et al. 1980). If the underlying gene action is nonadditive, the breakup of these...
Gene Action of New Mutations in Arabidopsis thaliana
; ...reducing height at flowering, additive gene action accounted for the expression of the...of new mutations on fitness, and the gene action of new mutations. Recent empirical studies...There is increasing interest in the gene action of mutations in terms of the dominance...
Heterosis for Biomass-Related Traits in Arabidopsis Investigated by Quantitative Trait Loci Analysis of the Triple Testcross Design With Recombinant Inbred Lines
; ...of heterotic QTL, (ii) characterizing their mode of gene action, and (iii) testing for presence of epistatic effects...and/or epistasis being presumably the main types of gene action. (ProQuest: ... denotes formulae omitted.) THE improved...heterosis are based on dominance and overdominance ...
Quantitative Modeling of Arabidopsis Development1[w]
; ...over time in a seemingly complex manner. This changing form provides the context of gene action while at the same time being under the control of gene action. To understand this process quantitatively, we first need to identify and measure the...
Gene action and cancer in eye lens.
; Gene action and cancer in eye lens The lens of the eye is an unusual tissue, constructed for transparency and lacking a blood vessel system...