The Protective Role of Melanin Against UV Damage in Human Skin[dagger]

From: Photochemistry and Photobiology | Date: May 1, 2008| Author: | Copyright information

ABSTRACT

Human skin is repeatedly exposed to UVR that influences the function and survival of many cell types and is regarded as the main causative factor in the induction of skin cancer. It has been traditionally believed that skin pigmentation is the most important photoprotective factor , as melanin, besides functioning as a broadband UV absorbent, has antioxidant and radical scavenging properties. Besides, many epidemiological studies have shown a lower incidence for skin cancer in individuals with darker skin compared to those with fair skin. Skin pigmentation is of great cultural and ...

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