The Relationship between Cocaine Use and Human Papillomavirus Infections in HIV-Seropositive and HIV-Seronegative Women

From: Infectious Diseases in Obstetrics and Gynecology | Date: January 1, 2008| Author: Burk, Robert; D'Souza, Gypsyamber; Howard, Andrea A; Levine, Alexandra M; Massad, L Stewart; Palefsky, Joel M; Plankey, Michael; Strickler, Howard D; Watts, D Heather; Zhong, Ye; Minkoff, Howard | Copyright information

Objective. Animal data suggest that cocaine has an immunosuppressive effect, but no human studies have been conducted to assess the relation of cocaine use with human papillomavirus (HPV) infection, the viral cause of cervical cancer. Since both cocaine use and HPV infection are common among HIV-positive women, we sought to determine whether use of cocaine and/or crack influences the natural history of HPV among women with or at high risk of HIV. Methods. Women enrolled in the Women's Interag...

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