Luminal Starch Substrate "Brake" on Maltase-Glucoamylase Activity Is Located within the Glucoamylase Subunit1-3 From: The Journal of Nutrition | Date: April 1, 2008| Author: Ao, Zihua; Brayer, Gary D; Hamaker, Bruce R; Nichols, Buford L; Quaroni, Andrea; Robayo-Torres, Claudia C; Rose, David R; Sim, Lyann; Sterchi, Erwin E; Quezada-Calvillo, Roberto | Copyright American Institute of Nutrition Apr 2008. Provided by ProQuest LLC.Copyright information

Abstract

The detailed mechanistic aspects for the final starch digestion process leading to effective α-glucogenesis by the 2 mucosal α-glucosidases, human sucrase-isomaltase complex (SI) and human maltase-glucoamylase (MGAM), are poorly understood. This is due to the structural complexity and vast variety of starches and their intermediate digestion products, the poorly understood enzyme-substrate interactions occurring during the digestive process, and the limited knowledge...