Functional hypothalamic amenorrhea: Current view on neuroendocrine aberrations

From: Gynecological Endocrinology | Date: January 1, 2008| Author: Genazzani, Andrea Riccardo; Podfigurna-Stopa, Agnieszka; Warenik-Szymankiewicz, Alina; Meczekalski, Blazej | Copyright information

Abstract

Functional hypothalamic amenorrhea (FHA) is defined as a non-organic and reversible disorder in which the impairment of gonadotropin-releasing hormone (GnRH) pulsadle secretion plays a key role. There are main three types of FHA: stress-related amenorrhea, weight loss-related amenorrhea and exercise-related amenorrhea. The spectrum of GnRH-luteinizing hormone (LH) disturbances in FHA is very broad and includes lower mean frequency of LH pulses, complete absence of LH pulsatili...

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