Interaction between Smoking and Genetic Factors in the Development of Chronic Bronchitis From: American Journal of Respiratory and Critical Care Medicine | Date: March 1, 2008| Author: Dahlbà de Verdier, Maria Gerhardsson; Dominicus, Annica; Eriksson, Ulrika K; Higenbottam, Tim; Nihlà Pedersen, Nancy L; Svartengren, Magnus; ¤ © ck, Magnus; Hallberg, Jenny; n, Ulf | Copyright American Thoracic Society Mar 1, 2008. Provided by ProQuest LLC.Copyright information

Rationale: Smoking is a primary risk factor for chronic bronchitis, emphysema, and chronic obstructive pulmonary disease, but since not all smokers develop disease, it has been suggested that some individuals may be more susceptible to exogenous factors, such as smoking, and that this susceptibility could be genetically determined.

Objectives: The aim of the present study was to assess, in a population based sample of twins, the following: (1) to what extent genetic factors contribute ...

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