Hyperinsulinism in Infancy and Childhood: When an Insulin Level Is Not Always Enough From: Clinical Chemistry | Date: February 1, 2008| Author: Palladino, Andrew A; Bennett, Michael J; Stanley, Charles A | Copyright American Association for Clinical Chemistry Feb 2008. Provided by ProQuest LLC.Copyright information

BACKGROUND: Hypoglycemia in infants and children can lead to seizures, developmental delay, and permanent brain damage. Hyperinsulinism (HI) is the most common cause of both transient and permanent disorders of hypoglycemia. HI is characterized by dysregulated insulin secretion, which results in persistent mild to severe hypoglycemia. The various forms of HI represent a group of clinically, genetically, and morphologically heterogeneous disorders.

CONTENT: Congenital hyperinsulinism is...

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