Vitamin B-12 status is inversely associated with plasma homocysteine in young women with C677T and/or A1298C methylenetetrahydrofolate reductase polymorphisms

From: The Journal of Nutrition | Date: July 1, 2002| Author: Bailey, Lynn B; Duhaney, Robert L; Maneval, David R; Kauwell, Gail P A; Et al | Copyright information

Vitamin B-12 Status Is Inversely Associated with Plasma Homocysteine in Young Women with C677T and/or A1298C Methylenetetrahydrofolate Reductase Polymorphisms1

ABSTRACT Methylenetetrahydrofolate reductase (MTHFR) polymorphisms may negatively influence one-carbon metabolism and increase health risks in women of reproductive age. The effect of MTHFR single nucleotide polymorphisms at bp 677 and/or 1298 and differences in folate and vitamin B-12 status on plasma homocysteine concentratio...