Mapping Quantitative Trait Loci From a Single-Tail Sample of the Phenotype Distribution Including Survival Data

From: Genetics | Date: December 1, 2007| Author: Hoti, Fabian; ¤ ¤ à , Mikko J; Sillanpà | Copyright information

ABSTRACT

A new effective Bayesian quantitative trait locus (QTL) mapping approach for the analysis of single-tail selected samples of the phenotype distribution is presented. The approach extends the affected-only tests to single-tail sampling with quantitative traits such as the log-normal survival time or censored/selected traits. A great benefit of the approach is that it enables the utilization of multiple-QTL models, is easy to incorporate into different data designs (experimental...

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