Extensive Additivity of Gene Expression Differentiates Subspecies of the House Mouse

From: Genetics | Date: November 1, 2007| Author: Rottscheidt, Ruth; Harr, Bettina | Copyright information

ABSTRACT

We have studied different subspecies of the house mouse and their reciprocal F^sub 1^ hybrids to estimate the within-locus mode of inheritance for subspecies differences in gene expression in three tissues (brain, liver, and testis) of male mice. This study investigates the mode of inheritance in crosses at a larger taxonomic distance than has been previously systematically investigated. We found the vast majority of transcripts to be additively expressed with only a few trans...

Read all of this article with a FREE trial to HighBeam Research