Ex Vivo Perfused Larynx Model of Phonation: Preliminary Study

From: The Annals of Otology, Rhinology & Laryngology | Date: November 1, 2007| Author: Berke, Gerald S; Neubauer, Juergen; Berry, David A; Ye, Ming; Chhetri, Dinesh K | Copyright information

Objectives: Although excised laryngeal models and physical models of the larynx are important in the study of laryngeal dynamics, they cannot be used to study the influence of neuromuscular contraction on vocal fold vibration, especially with regard to the thyroarytenoid muscle. Our aim was to develop an ex vivo larynx model of phonation, and combine the benefits of the in vivo and excised laryngeal models to the ex vivo situation.

Methods: Three canine larynges were surgically removed...