Fluorescence Single-Molecule Counting Assays for High-Sensitivity Detection of Cytokines and Chemokines From: Clinical Chemistry | Date: November 1, 2007| Author: | Copyright American Association for Clinical Chemistry Nov 2007. Provided by ProQuest LLC.Copyright information

Haoqun Qiu,1 Evan P. Ferrell,1 Niamh Nolan,2 Bruce H. Phelps,2 Raymond Tabibtazar,2 Duncan H. Whitney,1* and Eric A. Nalefski (1 U.S. Genomics, Woburn, MA;2 Aviir, Inc., Palo Alto, CA;* address correspondence to this author at: U.S. Genomics, 12 Gill St., Ste. 4700, Woburn, MA 01801; fax 781-938-0060, e-mail dwhitney@usgenomics.com)

A recent focus in clinical immunodiagnostics is to improve sensitivity of assays for rare circulating protein biomarkers. The ability to detect low concentrations of certain biomarkers translates to diagnosis of disease at an earlier stage, which can positively ...