Comparison of adenosine triphosphate and dipyridamole in diagnosis by thallium-201 myocardial scintigraphy

The Journal of Nuclear Medicine | April 1, 1997| | Copyright

We examined whether 21TI myocardial scintigraphy with intravenous infusion of adenosine triphosphate (ATP) can be substituted for dipyridamole (DIP) in the diagnosis of coronary artery disease (CAD). Methods: The coronary flow reserve (CFR) during intravenous infusion of ATP (0.10-0.20 mg/kg/min) was compared with that during intravenous infusion of DIP (0.56 mg/kg) using a Doppler flow wire in 19 subjects with normal coronary arteries. The highest CFR level was found in the ATP dose range of 0.164.20 mg/kg/min. The CFR at the ATP dose of 0.16 mg/kg/min was significantly higher than that ...

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