The serum anion gap

Archives of Pathology & Laboratory Medicine | June 1, 1997| | Copyright

Objective.-To compare the anion gap (calculated as the sodium concentration minus the sum of the chloride and total carbon dioxide concentrations) reference interval for three automated chemistry analyzers.

Design.-We measured serum sodium, chloride, and total carbon dioxide on aliquoted specimens using three commercial instruments. Quality control and proficiency survey materials were run to ensure that the analyzers were functioning optimally.

Setting-Three separate clinical laboratories affiliated with one university medical center participated in the study.

Participants.-Healthy ...

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