Testing the Extreme Value Domain of Attraction for Distributions of Beneficial Fitness Effects

From: Genetics | Date: August 1, 2007| Author: Beisel, Craig J; Rokyta, Darin R; Wichman, Holly A; Joyce, Paul | Copyright information

ABSTRACT

In modeling evolutionary genetics, it is often assumed that mutational effects are assigned according to a continuous probability distribution, and multiple distributions have been used with varying degrees of justification. For mutations with beneficial effects, the distribution currently favored is the exponential distribution, in part because it can be justified in terms of extreme value theory, since beneficial mutations should have fitnesses in the extreme right tail of t...

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