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Phosphoinositide Signaling in Unicellular Eukaryotes
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The review considers the up to date achievements in the role of membrane phosphoinositides and keys enzymes of the lipid branch of the phosphoinositide signal pathway (PI-pathway) in unicellular eukaryotes. Particular attention is paid to mechanisms of phospholipase C (PLC) activation and the PLC interaction both with cell surface receptors and with the effector cytoplasm targets. The role of protein kinase C (PKC) in intracellular signaling and the relationship of the PI-pathway key enzymes ...
Related newspaper, magazine, and journal articles from HighBeam Research
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Increased translocation of cardiac protein kinase C (beta)2 accompanies mild cardiac hypertrophy in rats fed saturated fat
The Journal of Nutrition
; Biochemical and Molecular Actions of Nutrients Research Communication Increased Translocation of Cardiac Protein Kinase C 132 Accompanies Mild Cardiac Hypertrophy in Rats Fed Saturated Fat1 ABSTRACT Signal transduction through protein kinase C (PKC) (beta)2 may modulate cardiac hypertrophy in
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Slow and prolonged activation of the p47 protein kinase during hypersensitive cell death in a culture of tobacco cells
Plant Physiology
; Kaoru Suzuki*, Akira Yano1, and Hideaki Shinshi To investigate the involvement of protein kinases in the signaling cascade that leads to hypersensitive cell death, we used a previously established system in which a fungal elicitor, xylanase from Trichoderma viride (TvX), induces a hypersensitive
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An antisense of protein kinase c-zeta inhibits proliferation of human airway smooth muscle cells
American Journal of Respiratory Cell and Molecular Biology
; We hypothesized that an atypical isoform of protein kinase (PK) C, PKC is essential for proliferation of human airway smooth muscle CHASM) cells in primary culture. Recombinant replication-deficient El-deleted adenoviruses (100 plaque-forming units [pfu]/cell) expressing the antisense of PKC-@ and
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Researchers are getting specific about protein kinase inhibitora
The Scientist
; HOT PAPERS | Study finds that reagents are largely overrated In signal transduction research, protein kinase inhibitors help scientists tease out the vagaries of complex signaling pathways, but anecdotal evidence suggests that they are flawed tools at best, lacking the specificity necessary to draw
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Calcium signaling through protein kinases. The Arabidopsis calcium-dependent protein kinase gene family
Plant Physiology
; Calcium Signaling through Protein Kinases. The Arabidopsis Calcium-Dependent Protein Kinase Gene Family1 In plants, numerous Ca^sup 2stimulated protein kinase activities occur through calcium-dependent protein kinases (CDPKs). These novel calcium sensors are likely to be crucial mediators of
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Expression of a gibberellin-induced leucine-rich repeat receptor-like protein kinase in deepwater rice and its interaction with kinase-associated protein phosphatase
Plant Physiology
; Expression of a Gibberelln-Induced Leucine-Rich Repeat Receptor-Like Protein Kinase in Deepwater Rice and Its Interaction with Kinase-Associated Protein Phosphatase' We identified in deepwater rice (Oryza sativa L.) a gene encoding a leucine-rich repeat receptor-like transmembrane protein kinase,
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The salt stress-inducible protein kinase gene, Esi47, from the salt-tolerant wheatgrass Lophopyrum elongatum is involved in plant hormone signaling
Plant Physiology
; The Salt Stress-Inducible Protein Kinase Gene, Esi47, from the Salt-Tolerant Wheatgrass Lophopyrum elongatum Is Involved in Plant Hormone Signaling) Protein kinases play a central role in signal transduction in all organisms and to study signal transduction in response to salt stress we have
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Osmotic stress induces rapid activation of a salicylic acid-induced protein kinase and a homolog of protein kinase ASK1 in tobacco cells
Plant Cell
; In tobacco cells, osmotic stress induced the rapid activation of two protein kinases that phosphorylate myelin basic protein. Immunological studies demonstrated that the 48-kD kinase is the salicylic acid-induced protein kinase (SIPK), a member of the mitogen-activated protein kinase family. SIPK
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Gibberellin/abscisic acid antagonism in barley aleurone cells: Site of action of the protein kinase PKABA1 in relation to gibberellin signaling molecules
Plant Cell
; The antagonism between gibberellins (GA) and abscisic acid (ABA) is an important factor regulating the developmental transition from embryogenesis to seed germination. In barley aleurone layers, the expression of genes encoding alpha-amylases and proteases is induced by GA but suppressed by ABA. It
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Localization and kinetics of protein kinase C-epsilon anchoring in cardiac myocytes
Biophysical Journal
; ABSTRACT Protein kinase C-epsilon (PKC-epsilon) plays a central role in cardiac cell signaling, but mechanisms of translocation and anchoring upon activation are poorly understood. Conventional PKC isoforms rely on a rapid Ca^sup 2mediated recruitment to cell membranes, but this mechanism cannot be
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