Simultaneous Analysis of D- and L-Serine in Cerebrospinal Fluid by Use of HPLC

Clinical Chemistry | August 1, 2007| | Copyright

Background: D-Serine is a coagonist for the glycine-binding site of the N-methyl-D-aspartate receptors and has been implicated in various neuropsychiatric functions such as learning, memory, and nociception, as well as schizophrenia and Alzheimer disease. We developed an HPLC method for D- and L-serine in cerebrospinal fluid (CSF).

Methods: The dabsylated racemic serine peak, automatically collected using a previously reported HPLC separation process for CSF amino acids, was desalted and subjected to a chiral resolution HPLC step with a Sumichiral column using an ultraviolet-visible detector.

Read all of this article with a FREE trial to HighBeam Research

Related newspaper, magazine, and trade journal articles from HighBeam Research

(Including press releases, facts, information, and biographies)

Exhibition marks the life and times of our decorated army icon ; Henry Parker, a great, great nephew of General Sir Redvers Buller, will open an exhibition in Crediton which tells the story of the town during the general's lifetime.
Newspaper article from: Express & Echo (Exeter UK) ; Henry Parker, a great, great nephew of General Sir Redvers Buller, will open an exhibition in Crediton...General Buller's military career. Redvers Henry Buller was born at Downes, Crediton...
The South African War, 1899-1902 -- stray thoughts on its history and its literature.
Magazine article from: Sabretache ; ...future Major-General Sir William Throsby Bridges...Transvaal, General Sir Redvers Henry Buller VC (1839-1908) sailed...in South Africa. Under Buller the British suffered serious...January 1900. General Buller's magnanimous offer...
Gazette: Anniversaries
Newspaper article from: The Independent - London ; ...Thomas Hardy, novelist, 1840; Sir Edward William Elgar, composer...Ostrovsky, playwright, 1886; Sir Redvers Henry Buller VC, general, 1908; Friedrich...actor, 1990. On this day: King Henry V of England married Catherine de...
Anniversaries
Newspaper article from: The Independent - London ; ...Besnard, painter and etcher, 1849; Sir Edward William Elgar, composer...Ostrovsky, playwright, 1886; Sir Redvers Henry Buller VC, general, 1908; Friedrich...actor, 1990. On this day: King Henry V of England married Catherine de...
Town tells the tale of its greatest hero ; Crediton has gone back in time to mark the centenary of the death of its greatest hero.
Newspaper article from: Express & Echo (Exeter UK) ; ...its greatest hero. General Sir Redvers Buller, VC, was buried in Crediton...life was opened in the town by Henry Parker, the general's great...exhibition describes General Buller's military career. Redvers Henry Buller was born at Downes...
Millennium anniversaries.
Magazine article from: Management Accounting (British) ; ...jubilation when General Sir Redvers Buller relieved the South African...same month, on 16 March, Sir Arthur Evans discovered...Metropolitan Police Force--Sir Robert Peel, died on 2...marriage bureau was opened by Henry Robinson in Threadneedle...
Playboy of the Western front?
Magazine article from: The Spectator ; ...wrote one of its future editors, Henry Wickham Steed, in 1908. 'We mould...Boers invaded Natal a year later, Sir Redvers Buller asked for him for his headquarters...LieutenantColonel (later Field Marshal) Henry Wilson. Wilson was a fellow Rifle...
Cross-dressers and cross-references Nicholas Bagnall enjoys this compendium of oddballs which doesn't let inconvenient truths get in the way of a good story
Newspaper article from: The Sunday Telegraph London ; ...as an amiable rogue, for this was the pseudonymous Henry Root who in 1980 posed as a fishmonger offering folding...faced reference- book style, as in the entry on Sir Redvers Buller, "of whom it has been said that his command of the...
ZULU: THE HEROISM AND TRAGEDY OF THE ZULU WAR
Magazine article from: The Spectator ; ...evening early,' Major Henry Spalding told Lieutenant...the Cape Colony governor Sir Bartle Frere, would also...s successor, General Sir Garnet Wolseley, thought...of men like Lt. Col. Redvers Buller, the aggressive and brave...

Find more facts and information related to the article "Simultaneous Analysis of D- and L-Serine in ..."