Mechanical Abrasion Improves Early Incorporation of Small Intestinal Submucosa/DISCUSSION

From: The American Surgeon | Date: July 1, 2007| Author: Davidson, J M; Et al; Nanney, L B; Poulose, B K; Rauth, Thomas P | Copyright information

It has been shown that gross incorporation of porcine-derived small intestinal submucosa (SiS) is limited at 2 weeks. This study evaluates a technique for improving the early incorporation of implanted eight-ply SiS. Six pigs underwent implantation of SiS on the peritoneal surface using three techniques: suture fixation of stock-perforated SiS, suture fixation of manually perforated SiS, and suture fixation of stock-perforated SiS to mechanically abraded peritoneum. Gross incorporation was ev...

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