Sex-Specific Viability, Sex Linkage and Dominance in Genomic Imprinting

Genetics | June 1, 2007| | Copyright

ABSTRACT

Genomic imprinting is a phenomenon by which the expression of an allele at a locus depends on the parent of origin. Two different two-locus evolutionary models are presented in which a second locus modifies the imprinting status of the primary locus, which is under differential se lection in males and females. In the first model, a modifier allele that imprints the primary locus invades the population when the average dominance coefficient among females and males is >½ and selection is weak. The condition for invasion is always heavily contingent upon the extent of dominance. ...

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