A Primary Assembly of a Bovine Haplotype Block Map Based on a 15,036-Single-Nucleotide Polymorphism Panel Genotyped in Holstein-Friesian Cattle From: Genetics | Date: June 1, 2007| Author: Et al; Hawken, Rachel J; Hobbs, Matthew; Zenger, Kyall R; Khatkar, Mehar S | Copyright Genetics Society of America Jun 2007. Provided by ProQuest LLC.Copyright information

ABSTRACT

Analysis of data on 1000 Holstein-Friesian bulls genotyped for 15,036 single-nucleotide polymorphisms (SNPs) has enabled genomewide identification of haplotype blocks and tag SNPs. A final subset of 9195 SNPs in Hardy-Weinberg equilibrium and mapped on autosomes on the bovine sequence assembly (release Btau 3.1) was used in this study. The average intermarker spacing was 251.8 kb. The average minor allele frequency (MAF) was 0.29 (0.05-0.5). Following recent precedents in huma...

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