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Quantitation of Plasma Cells in Bone Marrow Aspirates by Flow Cytometric Analysis Compared With Morphologic Assessment
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Context.-Accurate quantitation of bone marrow plasma cells is an important component in the diagnosis and post-treatment assessment of plasma cell dyscrasias. Although flow cytometry is sometimes used for this purpose and can rapidly evaluate many cells, the accuracy of flow-based plasma cell quantitation compared with morphologic assessment (currently the gold standard) is uncertain as direct comparison studies have not been previously reported.
Objective.-To determine how percentages...
Related newspaper, magazine, and journal articles from HighBeam Research
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Multiple myeloma
Rehabilitation Oncology
; What is Multiple Myeloma (MM)? A plasma cell neoplasm Plasma Cell Neoplasms Plasma cell cells made by lymphocytes called the B-cells when B-cells respond to an infection, they mature and change into plasma cells Function: produce and release immunoglobulins (antibodies), proteins that fight
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Intracranial plasma cell granuloma
Neurology India
; Introduction Plasma cell granuloma (PCG) is a rare form of idiopathic inflammatory pseudotumor, characterized by a benign proliferation consisting predominantly of plasma cells and reticuloendothelial elements.[1] Very few cases of primary PCG of the central nervous system are reported.[234] We
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Pathologic quiz case: An 86-year-old woman with refractory anemia
Archives of Pathology & Laboratory Medicine
; The patient was an 86-year-old woman who was referred to our institution for evaluation of persistent refractory anemia and fatigue. Her immediate past medical history was remarkable for a recent hospitalization for pneumonia, which was successfully treated with antibiotics, and renal failure
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An unusual finding of plasma cell iron
Archives of Pathology & Laboratory Medicine
; A 56-year-old woman presented with cryptogenic liver cirrhosis, diabetes, hypertension, hypothyroidism, and myelodysplasia. She reported a history of splenectomy for idiopathic thrombocytopenic purpura 12 years earlier and 2 recent episodes of hepatic encephalopathy. She said she does not drink
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A Rosette by any other name. . .
Archives of Pathology & Laboratory Medicine
; A 43-year-old man presented with fatigue after thalidomide treatment for plasma cell myeloma, diagnosed 3 years previously. A bone marrow aspiration was performed. The bone marrow clot section showed a peculiar rosettelike pattern, with a vasculocentric arrangement of malignant plasma cells
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