Predictors of Ineffective Cough during a Chest Infection in Patients with Stable Amyotrophic Lateral Sclerosis

From: American Journal of Respiratory and Critical Care Medicine | Date: June 15, 2007| Author: Dà Marà Servera, Emilio; ­ ­ º az, Juan; n, Julio; s; Sancho, Jesà | Copyright information

Rationale: In patients with neuromuscular diseases, a chest infection is associated with a reduction in respiratory muscle function that may result in decreased cough effectiveness.

Objectives: To determine if a clinical or functional parameter in patients with amyotrophic lateral sclerosis (ALS) in a stable condition could predict spontaneous cough ineffectiveness during a respiratory tract infection.

Methods: Forty consecutive patients with ALS referred to our Respiratory Care...

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