E2F Regulates FASCIATA1, a Chromatin Assembly Gene Whose Loss Switches on the Endocycle and Activates Gene Expression by Changing the Epigenetic Status1[C][W][OA] From: Plant Physiology | Date: May 1, 2007| Author: Ramirez-Parra, Elena; Gutierrez, Crisanto | Copyright American Society of Plant Physiologists May 2007. Provided by ProQuest LLC.Copyright information

Maintenance of genome integrity depends on histone chaperone-mediated chromatin reorganization. DNA replicationassociated nucleosome deposition relies on chromatin assembly factor-1 (CAF-1). Depletion of CAF-1 in human cells leads to cell death, whereas in Arabidopsis (Arabidopsis thaliana), where it is involved in heterochromatin compaction and homologous recombination, plants are viable. The mechanism that makes the lack of CAF-1 activity compatible with development is not known. Here, we s...

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