Differences in Taurine Synthesis Rate among Dogs Relate to Differences in Their Maintenance Energy Requirement1-3

From: The Journal of Nutrition | Date: May 1, 2007| Author: | Copyright information

Abstract

Diet-induced (taurine deficiency) dilated cardiomyopathy is reported more in large than small dogs possibly because taurine biosynthesis rate (TBR) is lower in large than small dogs. The TBR in 6 mongrels (37.9 ± 2.1 kg) and 6 beagles (12.8 ± 0.4kg) was determined from the fractional dilution rate of urinary [1,2-^sup 2^H^sub 2^]-taurine, (d4-tau). All dogs were given a 15.6% protein, 0.60% sulfur amino acid (SAA) diet in amounts to maintain an ideal body condition score. After 3 mo, 14.6 mg/kg body weight of d4-tau was given orally and TBR determined from d4-tau to taurine ratio ...

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