RhBMP-7 accelerates the healing in distal tibial fractures treated by external fixation From: Journal of Bone and Joint Surgery | Date: February 1, 2007| Author: Et al; Flinkkilà Hyvà Lakovaara, M; ¤ ¶ , T; nen, P; Ristiniemi, J | Copyright British Editorial Society of Bone & Joint Surgery Feb 2007. Provided by ProQuest LLC.Copyright information

External fixation of distal tiilal fractures is often associated with delayed union. We have investigated whether union can be enhanced by using recombinant bone morphogenetlc protein-7 (rhBMP-7).

Osteoinduction with rhBMP-7 and bovine collagen was used in 20 patients with distal tibial fractures which had been treated by external fixation (BMP group). Healing of the fracture was compared with that of 20 matched patients In whom treatment was similar except that rhBMP-7 was not used.

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