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Fabrication and Characterization of a 0.5-mm Lutetium Oxyorthosilicate Detector Array for High-Resolution PET Applications
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With the increasing use of in vivo imaging in mouse models of disease, there are many interesting applications that demand imaging of organs and tissues with submillimeter resolution. Though there are other contributing factors, the spatial resolution in small-animal PET is still largely determined by the detector pixel dimensions. Methods: In this work, a pair of lutetium oxyorthosilicate (LSO) arrays with 0.5-mm pixels was coupled to multichannel photomultiplier tubes and evaluated for use ...
Related newspaper, magazine, and journal articles from HighBeam Research
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Fabrication and Characterization of a 0.5-mm Lutetium Oxyorthosilicate Detector Array for High-Resolution PET Applications
The Journal of Nuclear Medicine
; With the increasing use of in vivo imaging in mouse models of disease, there are many interesting applications that demand imaging of organs and tissues with submillimeter resolution. Though there are other contributing factors, the spatial resolution in small-animal PET is still largely determined
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Recent Advances in SPECT Imaging
The Journal of Nuclear Medicine
; SPECT is a rapidly changing field, and the past several years have produced new developments in both hardware technology and image-processing algorithms. At the component level there have been improvements in scintillators and photon transducers as well as a greater availability of semiconductor
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99mTc-MIBI scintimammography using a dedicated nuclear mammograph
The Journal of Nuclear Medicine
; ... programmable microprocessors. The readout electronics include correction maps for on-line energy correction and spatial uniformity. The small ... electronics have a dedicated memory space in which correction maps are loaded for on-line energy correction during acquisition to ...
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Virtual-Pinhole PET
The Journal of Nuclear Medicine
; We proposed and tested a novel geometry for PET system design analogous to pinhole SPECT called the virtual-pinhole PET (VP-PET) geometry to determine whether it could provide high-resolution images. Methods: We analyzed the effects of photon acolinearity and detector sizes on system resolution and
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Mid-infrared Microspectroscopy of Difficult Samples Using Near-Field Photothermal Microspectroscopy
Spectroscopy
; The authors discuss progress in near-field IR microspectroscopy using a photothermal probe and show how it can be applied to the spectroscopic characterization of real-world samples. Despite recent advances in Fourier transform-infrared (FT-IR) microspectroscopy and micro-attenuated total
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A Novel Approach to Multipinhole SPECT for Myocardial Perfusion Imaging
The Journal of Nuclear Medicine
; Myocardial perfusion imaging with SPECT remains critically important for diagnosing, assessing, and evaluating treatment of coronary artery disease. However, conventional rotational SPECT suffers from prolonged study times because of relatively low detection efficiency. We therefore have
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Evaluation of Novel Whole-Body High-Resolution Rodent SPECT (Linoview) Based on Direct Acquisition of Linogram Projections
The Journal of Nuclear Medicine
; Studies of the biodistribution of radiolabeled compounds in rodents frequently are performed during the process of development of new pharmaceutical drugs. This article presents the evaluation of a new whole-body animal SPECT system, called the Linoview SPECT system. Methods: Linoview SPECT is
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The effects of transient attention on spatial resolution and the size of the attentional cue
Perception and Psychophysics
; It has been shown that transient attention enhances spatial resolution, but is the effect of transient attention on spatial resolution modulated by the size of the attentional cue? Would a gradual increase in the size of the cue lead to a gradual decrement in spatial resolution? To test these
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NASA EARTH SCIENCE PROGRAM:MICHAEL F. GOODCHILD
Congressional Testimony
; ... researchers, companies, and agencies to produce maps. Images are used to record and assess the ... mapping is not generally available. Base maps made from remotely sensed images are being ... airborne as well as satellite sensors then all maps produced operationally by the U.S. Government ...
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Scintillation Crystal or Semiconductor [gamma]-Probes: An Open Debate/REPLY
The Journal of Nuclear Medicine
; TO THE EDITOR: The invited perspective of Mariani el al. (1) and the article of Classe et al. (2) deal with intraoperativc radioguided surgery, especially in sentinel lymph node detection. Without doubt, the principal characteristics of a high-performance intraoperative γ-probe in terms of
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