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Paramecium: An excitable cell with great potential
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HOW-TO-DO-IT
Paramecium, a single-celled ciliate, is an excitable cell. This protozoa's swimming behavior is well documented as a response to a variety of stimuli such as changes in pH, temperature and ion concentrations (Saimi & Kung 1980; Kung & Saimi 1982; Saimi et al. 1983). The cell membrane contains many proteins, including calcium, potassium and sodium ion channels. Channels allow ions to cross the cell membrane from areas of high ion concentration to areas of low conce...
Related newspaper, magazine, and journal articles from HighBeam Research
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Identification of Three Genes of Known Function Expressed by Alveolar Epithelial Type I Cells
American Journal of Respiratory Cell and Molecular Biology
; ... surfactant exocytosis in alveolar type ? cells in vitro and in vivo. News Physiol. Sci. 16:239-243. 4. Sartori. C., M. A. Matthay, and ... activator inhibitor 1: physiological and pathophysiological roles. News Physiol. Sci. 17:56-61. 30. Idell, S., K. K. James, E. G. Levin ...
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B Cells in Health and Disease
Mayo Clinic Proceedings
; B cells play a key role in regulating the immune system by producing antibodies, acting as antigen-presenting cells, providing support to other mononuclear cells, and contributing directly to inflammatory pathways. Accumulating evidence points to disruption of these tightly regulated processes in
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Recall Helper T Cell Response: T Helper 1 Cell-resistant Allergic Susceptibility without Biasing Uncommitted CD4 T Cells
American Journal of Respiratory and Critical Care Medicine
; Effector and memory T lymphocytes differ significantly, and there is no experimental evidence that memory cells are sufficient to render an otherwise normal individual susceptible to localized allergic inflammation. Furthermore, nothing is known about the kinetics of memory responses after
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Early induction of binucleated cells by ultraviolet A (UVA) radiation: A possible role of microfilaments
Photochemistry and Photobiology
; Early Induction of Binucleated Cells by Ultraviolet A (UVA) Radiation: A Possible Role of Microfilaments^^ ABSTRACT The effects of UVA (365 nm) radiation on the cellular distribution of F-actin and formation of binucleated cells have been studied using 3T3 Swiss albino mouse fibroblasts and V79
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Long-Term Deposition of Inhaled Antigen in Lung Resident CD11b^sup -^CD11c^sup +^ Cells
American Journal of Respiratory Cell and Molecular Biology
; In this study we report the characterization of a population of lung resident CD11b^sup -^CD11c^sup +^ cells that are able to take up inhaled antigen and retain it for extended periods of time. Ovalbumin conjugated to fluorescein-isothiocyanate (FITC-OVA) administered intranasally to mice was taken
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Perforin-independent CD8+ T-cell--mediated cytotoxicity of Alveolar epithelial cells in preferentially mediated by tumor necrosis (factor-alpha) relative insensitivity to Fas ligand
American Journal of Respiratory Cell and Molecular Biology
; CD8+ T cells appear to play an important pathophysiologic role in many inflammatory lung diseases. The primary effector function of this T-cell subset is cytolysis of virus-infected cells, and it is widely believed that there are two primary molecular mechanisms by which this occurs: the
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Proliferation and differentiation of Xenopus A6 cells under hypergravity as revealed by time-lapse imaging
In Vitro Cellular & Developmental Biology
; SUMMMRY Xenopus laevis A6 cells, which are cloned epithelial cells from the Xenopus kidney, differentiate into a dome structure when the cells reach confluence. We investigated the gravitational responses of A6 cellular motility during normal differentiation and differentiation under hypergravity
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Epstein-Barr virus latently infected cells are selectively deleted in simulated-microgravity cultures
In Vitro Cellular & Developmental Biology
; SUMMARY Rotating-wall vessels (RWVs) allow for the cultivation of cells in simulated microgravity. Previously, we showed that the cultivation of lymphoblastoid cells in simulated microgravity results in the suppression of Epstein-Barr virus (EBV) reactivation. To determine if the suppression
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Lipids in blood-brain barrier models in vitro II: Influence of glial cells on lipid classes and lipid fatty acids
In Vitro Cellular & Developmental Biology
; SUMMARY Lipids of brain tissue and brain microvascular endothelial cells contain high proportions of long-chain polyunsaturated fatty acids (long PUFAs). The blood-brain barrier (BBB) is formed by the brain endothelial cells under the inductive influence of brain cells, especially perivascular
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Naive and memory T cells migrate in comparable numbers through the normal rat lung: Only effector T Cells accumulate and proliferate in the lamina propria of the bronchi
American Journal of Respiratory Cell and Molecular Biology
; T cells reach the lung via the pulmonary and bronchial arteries that supply the alveolar and bronchial regions. Although these regions are differentially affected by T cell-mediated diseases, the migration of T-cell subsets in these two regions has not been studied. Naive, memory, and effector T
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