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Differential Expression of Kinase Genes in Primary Hyperparathyroidism: Adenoma Versus Normal and Hyperplastic Parathyroid Tissue
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* Context.-Differentiation between adenoma and hyperplasia or even normal parathyroid tissue is difficult and based mainly on the surgeon's skill. Exploration of genes that express differentially in these various tissues using microarrays and other sophisticated research tools will enable identification and perhaps development of new methods of perioperative diagnosis.
Objective.-To assemble a panel of kinase genes to differentiate parathyroid adenoma from normal and hyperplastic parat...
Related newspaper, magazine, and journal articles from HighBeam Research
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Differential Expression of Kinase Genes in Primary Hyperparathyroidism: Adenoma Versus Normal and Hyperplastic Parathyroid Tissue
Archives of Pathology & Laboratory Medicine
; * Context.-Differentiation between adenoma and hyperplasia or even normal parathyroid tissue is difficult and based mainly on the surgeon's skill. Exploration of genes that express differentially in these various tissues using microarrays and other sophisticated research tools will enable
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Validation study of intraoperative fine-needle aspiration of parathyroid tissue with measurement of parathyroid hormone levels using the rapid intraoperative assay.(Clinical report)
Baylor University Medical Center Proceedings
; Background: Surgical treatment of hyperparathyroidism relies on the ability to accurately identify parathyroid tissue. The use of intraoperative fine-needle aspiration (FNA) with measurement of intact parathyroid hormone level (iPTH-FNA) has been suggested as a useful adjunct and is evaluated in
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Risk of parathyromatosis after fine-needle aspiration / Discussion
The American Surgeon
; Reoperative surgery for hyperparathyroidism (HPT) is fraught with hazard. When preoperative imaging studies are inconclusive or patient comorbidities are extensive fine needle-aspiration (FNA) is helpful to confirm the presence of suspected parathyroid tissue in the neck. Some surgeons refrain from
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Relapsing Secondary Hyperparathyroidism Due to Multiple Nodular Formations After Total Parathyroidectomy with Autograft
The American Surgeon
; Total parathyroidectomy with autograft represents an optimal surgical technique in the treatment of secondary hyperparathyroidism. Relapsing hyperparathyroidism due to miliary-type nodular formations scattered over the autograft site represents a complication that is rarely described in the
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Kinase cDNA Clone Set.(Editor's Choice)
Bioscience Technology
; Kinase CloneSet[TM], a designated subset of over 500 full-length kinase cDNA clones, has been added to the OriGene Technologies TrueClone[TM] Collection product line. The Kinase CloneSet approaches the predicted 518 putative genes in the Kinome (Manning, G. et al., Science 298:1912, 2002) and
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Full-length kinase cDNA clones.(New Products)
Bioscience Technology
; Added to the TrueClone[TM] collection is the Kinase CloneSet[TM], a designated subset of over 500 full-length kinase cDNA clones. The company's TrueClone Collection of 20,000 full-length human cDNAs includes over 75% of the NM sequences in the NCBI RefSeq database and covers 6580% of the predicted
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Comparison of parathyroid imaging with technetium-99m-pertechnetate/sestamibi subtraction, double-phase technetium-99m-sestamibi and technetium-99m-sestamibi SPECT
The Journal of Nuclear Medicine
; The ability of 99mTc-pertechnetate/sestamibi subtraction, doublephase 99mTc-sestamibi and 99mTc-sestamibi SPECT imaging to localize abnormal parathyroid tissue was compared. Methods: Fifty-five consecutive patients had parathyroid imaging before surgery for hyperparathyroidism. Imaging consisted of
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Radioguided parathyroidectomy: Initial results of Hacettepe experience
Turkish Journal of Cancer
; ABSTRACT In 85-90% of the cases primary parathyroidism is caused by a single adenoma. In experienced hands the success of the standard parathyroidectomy is 95%. Recently, radio-guided parathyroidectomy offers an alternative to standard parathyroidectomy. The sensitivity of the sestamibi
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Editorial: The pathologist's intraoperative role during parathyroid surgery
Archives of Pathology & Laboratory Medicine
; Primary hyperparathyroidism is a relatively common disease, occurring in 25 to 50 per 100000 members of the population. During 2001 at the Massachusetts General Hospital, 148 successful parathyroid explorations for primary hyperparathyroidism were performed, largely by 2 surgeons. An additional 11
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DIRECT REVASCULARIZATION IS SUPERIOR FOR RAT PARATHYROID ALLOTRANSPLANTATION WITH FK506
The Annals of Otology, Rhinology & Laryngology
; Parathyroid gland allotransplantation has been a challenging goal for decades. Our objective was to optimize a parathyroid allotransplantation model for analysis of short-term or low-dose immunosuppressive regimens. Rats that had undergone parathyroidectomy received parathyroid allografts either by
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